After joining as faculty, I have focused exclusively on developing an implementation research program on point-of-care tests for HIV and related co-infections at McGill University.
My research programs and strategies have been evaluated in diverse marginalized populations in domestic and international settings: incarcerated populations in the United States, immigrants, injection drug users and men who have sex with men in Canada, sexually transmitted clinic attendees and pregnant women in India, healthcare workers and township populations of South Africa.
My research mission is to develop novel strategies and programs with rapid point-of-care tests, so as to inform and ultimately help change policies in the country of research, as well as internationally.
My research vision includes developing innovative strategies with oral HIV rapid tests (which include self-tests) and simultaneous testing strategies using several rapid tests for HIV and co-infections (i.e., Hepatitis C, Hepatitis B, Syphilis, CT, GC, Trich ) so as to rapidly test, treat and link patients to care, and evaluating biomarker-based and DNA/RNA based multiplex testing strategies for HIV and co-infections.
My current focus is on developing, innovating and evaluating innovative strategies for in home self-testing for HIV in South Africa, Canada, and India, and multiplexed programs (STI/HIV) synergized with mHealth (mobile health) for HIV related co-infections screening for Canada and India.
I have also been involved in knowledge synthesis and knowledge translation activities. I have conducted more than 26 systematic reviews and meta-analyses. These have helped inform global policy on point-of-care tests; most notably, those on oral HIV rapid tests, HIV self-tests, Hepatitis B, Hepatitis C and Syphilis CD4 based point-of-care tests.
Looking into the future, I will develop personalized programs of care for patients with HIV and co-infections focused on genetic screening, resistance testing with point-of-care assays and wearables, to improve the cascade from access to retention and monitoring in care. These programs will be developed for two groups: a) at risk populations in high, and middle income countries for HIV and co-infections and b) young women and their infants, in low and middle income countries for care through their reproductive years.